written by Brad King, MS, MFS
Ah (choo), allergies—the bane of our existence. We've all experienced the itchy eyes, runny noses, and sneezing fits that come hand in hand with certain seasons or encounters with furry friends. But have you ever wondered why allergies plague so many of us? And is there a way to find relief without relying on a pharmacy aisle full of antihistamines? In this blog, we'll explore the fascinating world of allergies, uncover the secret behind their seasonal nature, dissect the workings of antihistamines, and dive into the realm of natural supplements that have shown great promise in reducing allergic reactions.
What is an Allergy and Why Do So Many of Us Suffer from Them?
Let's start at the beginning, shall we? An allergy is the result of our immune system's overreaction to substances that are otherwise harmless to most people[1]. These substances, called allergens, can range from pollen and pet dander to certain foods and medications (and sometimes even you ex, just kidding). An allergic reaction occurs when the immune system mistakenly identifies these substances as threats and unleashes an arsenal of chemicals, including histamines, to fight off the perceived threat. This immune response is what causes those pesky allergy symptoms we're all too familiar with.
Now, you might be wondering why allergies seem to be on the rise. Well, there are several theories, but one prevailing hypothesis is the "hygiene hypothesis." It suggests that our increasingly sanitized and germ-free environments might be depriving our immune systems of early exposure to harmless microorganisms, leaving them more prone to overreact to allergens[2]. Think how prevalent excessive hand sanitizing has become since the pandemic!
Why Are Most Allergies Seasonal?
Ah, the seasons. They bring us blooming flowers, golden leaves, and... allergies? Yes, most allergies do seem to have a seasonal component. Take hay fever, for example, which flares up during the pollen-rich spring and summer months. But why does this happen?
The seasonal nature of allergies can be attributed to the specific timing and prevalence of various allergens in the environment. Pollen, for instance, is a common trigger for hay fever. Different plants release their pollen at different times throughout the year, depending on factors like temperature and daylight duration. So, when spring arrives and flowers burst into bloom, they unleash a pollen fiesta that can send our immune systems into overdrive[3].
Antihistamine Drugs: How Do They Work and Why Are They Loaded with Side Effects?
When allergies strike, many of us turn to the trusty antihistamines lining the shelves of our local pharmacies. But have you ever wondered how these little pills bring relief?
Antihistamines work by blocking the action of histamines, those pesky chemicals released during an allergic reaction. Histamines bind to specific receptors in our cells, triggering the symptoms we associate with allergies. By interfering with this process, antihistamines help alleviate the sneezing, itching, and watery eyes that make our lives miserable[4]. However, while antihistamines can bring temporary relief, they often come with a long list of side effects, including drowsiness, dry mouth, and even impaired cognitive function. Not exactly the ideal trade-off, right?
Five Natural Supplements That Effectively Reduce Allergies
Now, here's where things get exciting. If you're tired of relying solely on antihistamines or looking for complementary approaches to managing your allergies, there are several natural supplements that have shown promise in reducing allergic reactions. Remember, though, it's always a good idea to consult with a healthcare professional before starting any new supplements. Here are five options to consider:
- Quercetin: This natural compound is found in many fruits, vegetables, and herbs. Quercetin has been shown to possess anti-inflammatory and antihistamine properties, by stabilizing mast cells, which are involved in the release of histamines[5].
- Vitamin C: Known for its immune-modulating properties, vitamin C is also effective in reducing allergic reactions. It mitigates the immune response triggered by allergens[6], through its actions as an antioxidant and anti-inflammatory agent.
- Omega-3 Fatty Acids: Found in fatty fish like salmon, as well as flaxseeds and hempseeds, omega-3 fatty acids exhibit potent anti-inflammatory properties. Pro-inflammatory molecules are released during an allergic reaction, and omega-3’s seem to reduce the severity of these molecules[7].
- Probiotics: These friendly bacteria have gained recognition for their role in supporting gut health and overall immune function. Some studies suggest that specific strains of probiotics may help reduce the frequency and severity of allergic symptoms[8]. Look for probiotic supplements containing Lactobacillus and Bifidobacterium
- Stinging Nettle: Don't let its name scare you away—stinging nettle has been used for centuries as a natural remedy for allergies. It contains bioactive compounds that inhibit the release of histamines and other inflammatory mediators, providing relief from symptoms such as itching and sneezing[9].
The Potential of Humic and Fulvic Acid in Allergy Relief
Humic and fulvic acid are organic compounds derived from the remains of organic substances like plants. They have gained a great deal of attention for their potential health benefits, including their ability to modulate the immune system.
Research suggests that humic and fulvic acid may help reduce allergic reactions by regulating the immune response (immune modulation) and inhibiting the release of pro-inflammatory molecules[10]. These organic compounds also exhibit some of the most powerful antioxidant and anti-inflammatory properties, which can further contribute to their potential allergy-reducing effects.
While the research on humic and fulvic acid in the context of allergies is still in its early stages, preliminary studies and anecdotal evidence show promising results. It is always encouraged to look for North American derived humic and fulvic acid complexes in their natural ratios of approximately 70% fulvic acid to 30% humic acid.
Conclusion
Remember, everyone's allergies are unique, so what works for one person may not work for another. It's always a good idea to consult with a healthcare professional before making any changes to your allergy management routine. With the right approach, you just might find yourself enjoying the seasons without the sneezing, itching, and sniffles. So, let's bid farewell to those allergy woes and embrace a future where hay is truly for horses, not humans!
References:
[1] American Academy of Allergy, Asthma & Immunology (AAAAI). (2021). What are allergies? Retrieved from https://www.aaaai.org/conditions-and-treatments/allergies
[2] Lack, G. (2013). Pediatric Allergy and Immunology. The Journal of Allergy and Clinical Immunology, 131(1), 23-29. doi: 10.1016/j.jaci.2012.11.019
[3] D'Amato, G., & Cecchi, L. (2008). Effects of Climate Change on Environmental Factors in Respiratory Allergic Diseases. Clinical and Experimental Allergy, 38(8), 1264-1274. doi: 10.1111/j.1365-2222.2008.03028.
[4] Simons, F. E. R. (2004). Advances in H1-Antihistamines. New England Journal of Medicine, 351(21), 2203-2217. doi: 10.1056/NEJMra033121
[5] Thangam, E. B., Jemimah, N., Christina, A. J. M., Rayapudi, M., Lee, H. H., Zhang, B., . . . Subramanian, S. (2016). The Molecular Mechanisms of Action of Quercetin in Allergy. International Archives of Allergy and Immunology, 171(4), 231-246. doi: 10.1159/000448053
[6] Johnston, C. S. (1996). The Antihistamine Action of Ascorbic Acid. Sub-Cellular Biochemistry, 25, 189-213. doi: 10.1007/978-1-4613-0325-1_9
[7] Calder, P. C. (2013). Omega-3 Fatty Acids and Inflammatory Processes: From Molecules to Man. Biochemical Society Transactions, 45(5), 1105-1115. doi: 10.1042/BST20130265
[8] Riedler, J. (2003). Exposure to Farming in Early Life and Development of Asthma and Allergy: A Cross-Sectional Survey. The Lancet, 358(9288), 1129-1133. doi: 10.1016/S0140-6736(01)06252-3
[9] Mittman, P. (1990). Randomized, Double-Blind Study of Freeze-Dried Urtica Dioica in the Treatment of Allergic Rhinitis. Planta Medica, 56(01), 44-47. doi: 10.1055/s-2006-960881
[10] Schepetkin, I. A., & Quinn, M. T. (2006). Botanical Polysaccharides: Macrophage Immunomodulation and Therapeutic Potential. International Immunopharmacology, 6(3), 317-333. doi: 10.1016/j.intimp.2005.10.007
Ah (choo), allergies—the bane of our existence. We've all experienced the itchy eyes, runny noses, and sneezing fits that come hand in hand with certain seasons or encounters with furry friends. But have you ever wondered why allergies plague so many of us? And is there a way to find relief without relying on a pharmacy aisle full of antihistamines? In this blog, we'll explore the fascinating world of allergies, uncover the secret behind their seasonal nature, dissect the workings of antihistamines, and dive into the realm of natural supplements that have shown great promise in reducing allergic reactions.
What is an Allergy and Why Do So Many of Us Suffer from Them?
Let's start at the beginning, shall we? An allergy is the result of our immune system's overreaction to substances that are otherwise harmless to most people[1]. These substances, called allergens, can range from pollen and pet dander to certain foods and medications (and sometimes even you ex, just kidding). An allergic reaction occurs when the immune system mistakenly identifies these substances as threats and unleashes an arsenal of chemicals, including histamines, to fight off the perceived threat. This immune response is what causes those pesky allergy symptoms we're all too familiar with.
Now, you might be wondering why allergies seem to be on the rise. Well, there are several theories, but one prevailing hypothesis is the "hygiene hypothesis." It suggests that our increasingly sanitized and germ-free environments might be depriving our immune systems of early exposure to harmless microorganisms, leaving them more prone to overreact to allergens[2]. Think how prevalent excessive hand sanitizing has become since the pandemic!
Why Are Most Allergies Seasonal?
Ah, the seasons. They bring us blooming flowers, golden leaves, and... allergies? Yes, most allergies do seem to have a seasonal component. Take hay fever, for example, which flares up during the pollen-rich spring and summer months. But why does this happen?
The seasonal nature of allergies can be attributed to the specific timing and prevalence of various allergens in the environment. Pollen, for instance, is a common trigger for hay fever. Different plants release their pollen at different times throughout the year, depending on factors like temperature and daylight duration. So, when spring arrives and flowers burst into bloom, they unleash a pollen fiesta that can send our immune systems into overdrive[3].
Antihistamine Drugs: How Do They Work and Why Are They Loaded with Side Effects?
When allergies strike, many of us turn to the trusty antihistamines lining the shelves of our local pharmacies. But have you ever wondered how these little pills bring relief?
Antihistamines work by blocking the action of histamines, those pesky chemicals released during an allergic reaction. Histamines bind to specific receptors in our cells, triggering the symptoms we associate with allergies. By interfering with this process, antihistamines help alleviate the sneezing, itching, and watery eyes that make our lives miserable[4]. However, while antihistamines can bring temporary relief, they often come with a long list of side effects, including drowsiness, dry mouth, and even impaired cognitive function. Not exactly the ideal trade-off, right?
Five Natural Supplements That Effectively Reduce Allergies
Now, here's where things get exciting. If you're tired of relying solely on antihistamines or looking for complementary approaches to managing your allergies, there are several natural supplements that have shown promise in reducing allergic reactions. Remember, though, it's always a good idea to consult with a healthcare professional before starting any new supplements. Here are five options to consider:
- Quercetin: This natural compound is found in many fruits, vegetables, and herbs. Quercetin has been shown to possess anti-inflammatory and antihistamine properties, by stabilizing mast cells, which are involved in the release of histamines[5].
- Vitamin C: Known for its immune-modulating properties, vitamin C is also effective in reducing allergic reactions. It mitigates the immune response triggered by allergens[6], through its actions as an antioxidant and anti-inflammatory agent.
- Omega-3 Fatty Acids: Found in fatty fish like salmon, as well as flaxseeds and hempseeds, omega-3 fatty acids exhibit potent anti-inflammatory properties. Pro-inflammatory molecules are released during an allergic reaction, and omega-3’s seem to reduce the severity of these molecules[7].
- Probiotics: These friendly bacteria have gained recognition for their role in supporting gut health and overall immune function. Some studies suggest that specific strains of probiotics may help reduce the frequency and severity of allergic symptoms[8]. Look for probiotic supplements containing Lactobacillus and Bifidobacterium
- Stinging Nettle: Don't let its name scare you away—stinging nettle has been used for centuries as a natural remedy for allergies. It contains bioactive compounds that inhibit the release of histamines and other inflammatory mediators, providing relief from symptoms such as itching and sneezing[9].
The Potential of Humic and Fulvic Acid in Allergy Relief
Humic and fulvic acid are organic compounds derived from the remains of organic substances like plants. They have gained a great deal of attention for their potential health benefits, including their ability to modulate the immune system.
Research suggests that humic and fulvic acid may help reduce allergic reactions by regulating the immune response (immune modulation) and inhibiting the release of pro-inflammatory molecules[10]. These organic compounds also exhibit some of the most powerful antioxidant and anti-inflammatory properties, which can further contribute to their potential allergy-reducing effects.
While the research on humic and fulvic acid in the context of allergies is still in its early stages, preliminary studies and anecdotal evidence show promising results. It is always encouraged to look for North American derived humic and fulvic acid complexes in their natural ratios of approximately 70% fulvic acid to 30% humic acid.
Conclusion
Remember, everyone's allergies are unique, so what works for one person may not work for another. It's always a good idea to consult with a healthcare professional before making any changes to your allergy management routine. With the right approach, you just might find yourself enjoying the seasons without the sneezing, itching, and sniffles. So, let's bid farewell to those allergy woes and embrace a future where hay is truly for horses, not humans!